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Article

Genetic polymorphism at codon 10 of the transforming growth factor-β1 gene in patients with alcoholic liver cirrhosis.

The Korean journal of hepatology - 1 Mar 2011

Lee Jong Joon, Park Soo Kyung, Kwon Oh Sang, Won In Sik, Kim Dong Kyu, Jung Young Kul, Ku Yang Suh, Kim Yun Soo, Choi Duck Joo, Kim Ju Hyun

Abstract excerpt

BACKGROUND/AIMS: Transforming growth factor beta1 (TGF-β1) is a key cytokine in the production of extracellular matrix. A genetic polymorphism at codon 10 of the TGF-β1 gene is associated with liver fibrosis. We investigated the effect of genetic polymorphisms at codon 10 on the development of alcoholic liver cirrhosis (ALC). METHODS: In total, 119 controls and 182 patients with ALC, were enrolled in the study....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21494076
DOI: 10.3350/kjhep.2011.17.1.37
PMCID: PMC3304620

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