Article
Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients.
The Kaohsiung journal of medical sciences - 1 Jun 2014
Yang An-Ming, Wen Li-Li, Yang Chang-Shyue, Wang Sun-Chong, Chen Chien-Sheng, Bair Ming-Jong
Abstract excerpt
Alcoholic liver cirrhosis is a severe form of alcohol-related liver damage. More than 95% of heavy drinkers develop a fatty liver, but only 35% of them develop cirrhosis. We postulate that genetic factors may play a role in this difference. Genetic polymorphisms of the cytokine genes may influence Kupffer cells cytokine genes expression. In this study, we evaluated the promoter polymorphisms of interleukin (IL)...
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