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Article

A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men.

PloS one - 1 Jan 2016

Novo-Veleiro Ignacio, Cieza-Borrella Clara, Pastor Isabel, Chamorro Antonio-Javier, Laso Francisco-Javier, González-Sarmiento Rogelio, Marcos Miguel

Abstract excerpt

BACKGROUND: Genetic polymorphisms in the RAS gene family are associated with different diseases, which may include alcohol-related disorders. Previous studies showed an association of the allelic variant rs26907 in RASGRF2 gene with higher alcohol intake. Additionally, the rs61764370 polymorphism in the KRAS gene is located in a binding site for the let-7 micro-RNA family, which is potentially involved in...

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Source

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Identifiers

PMID: 27992614
DOI: 10.1371/journal.pone.0168685
PMCID: PMC5167392

Genes

RASGRF2
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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