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Article

Cytokine gene polymorphisms in heavy drinkers with and without decompensated liver disease: a case-control study.

The American journal of gastroenterology - 1 Dec 2008

Gleeson Dermot, Bradley Martin P, Jones Jayne, Peck Robert J, Bond Sarah K, Teare M Dawn, Duff Gordon W

Abstract excerpt

BACKGROUND: Twin studies have suggested some genetic predisposition to alcoholic liver disease (ALD). Cytokines may be involved in ALD pathogenesis. Several cytokine genes contain functionally significant polymorphisms. Associations between ALD and polymorphisms on the interleukin-1 (IL-1), IL-10, and tumor necrosis factor-alpha (TNF-alpha) genes have been reported but not confirmed. OBJECTIVE: Comparison of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19086955
DOI: 10.1111/j.1572-0241.2008.02150.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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