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Article

Polymorphisms in the transforming growth factor-beta gene (TGF-beta) and the risk of advanced alcoholic liver disease.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2005

Oliver Javier, Agúndez José A G, Morales Sonia, Fernández-Arquero Miguel, Fernández-Gutierrez Benjamín, de la Concha Emilio G, Díaz-Rubio Manuel, Martín Javier, Ladero José M

Abstract excerpt

BACKGROUND/AIMS: There are wide interindividual differences in the risk of developing alcoholic cirrhosis. Transforming growth factor beta(1) (TGF-beta(1)) is the main cytokine involved in liver fibrogenesis. The TGF-beta(1) gene is polymorphic at several sites and these polymorphisms are probably related to differences in the rate of TGF-beta(1) synthesis. Our aim has been to analyse the influence of the...

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PMID: 16162149
DOI: 10.1111/j.1478-3231.2005.01150.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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