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Article

Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study.

Alcoholism, clinical and experimental research - 1 Dec 2009

Saiz Pilar A, Garcia-Portilla Maria P, Florez Gerardo, Corcoran Paul, Arango Celso, Morales Blanca, Leza Juan C, Alvarez Sandra, Díaz Eva M, Alvarez Victoria, Coto Eliecer, Nogueiras Luis, Bobes Julio

Abstract excerpt

BACKGROUND: There is growing evidence for involvement of pro-inflammatory cytokines in alcohol dependence. The aim of this study was to investigate whether 4 functionally relevant polymorphisms of the interleukin-1 (IL-1) and tumor necrosis factor-alpha genes were associated with alcohol dependence and with measures of clinical severity and treatment outcome. METHODS: Two hundred alcohol-dependent (AD) patients...

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PMID: 19764937
DOI: 10.1111/j.1530-0277.2009.01058.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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