Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker.

Alcoholism, clinical and experimental research - 1 May 2008

Nguyen-Khac Eric, Houchi Hakim, Daoust Martine, Dupas Jean Louis, Naassila Mickaël

Abstract excerpt

BACKGROUND: This study investigated whether genetic polymorphisms in the tumor necrosis factor alpha (TNFalpha) gene's promoter region play a role in severe acute alcoholic hepatitis (AAH). METHODS: One-hundred and fifty patients (58 AAH patients, 45 cirrhosis group free-AAH, 47 healthy group) were genotyped for 3 TNFalpha polymorphisms (-238, -308, -863) using a polymerase chain reaction-restriction fragment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Hormones
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Liver Cirrhosis

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 18336639
DOI: 10.1111/j.1530-0277.2008.00629.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker.PMID 18336639Read ↗

A study on the TNF-alpha system in Caucasian Spanish patients with alcoholic liver disease.Semantic proximity Read ↗

-238 G>A polymorphism of tumor necrosis factor alpha gene (TNFA) is associated with alcoholic liver cirrhosis in alcoholic Spanish men.Semantic proximity Read ↗

Association of tumor necrosis factor-alpha gene promoter polymorphisms with acute viral hepatitis in the Indian population.Semantic proximity Read ↗

Tumor necrosis factor polymorphisms and alcoholic liver disease: a HuGE review and meta-analysis.Semantic proximity Read ↗

Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients.Semantic proximity Read ↗

Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease?Semantic proximity Read ↗

Tumor Necrosis Factor Alpha 308 G/A Single Nucleotide Polymorphism and Susceptibility to Hepatocellular Carcinoma Via Hepatitis B Infection.Semantic proximity Read ↗

Associations between the tumor necrosis factor-α gene and interleukin-10 gene polymorphisms and risk of alcoholic liver disease: A meta-analysis.Semantic proximity Read ↗

Associations of tumour necrosis factor alpha promoter polymorphisms at position -308 and -238 with clinical characteristics of chronic hepatitis C.Semantic proximity Read ↗

Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease.Semantic proximity Read ↗

A tumor necrosis factor-alpha (TNF-alpha) promoter polymorphism is associated with chronic hepatitis B infection.Semantic proximity Read ↗

Tumor necrosis factor alpha promoter polymorphisms at position -308 in Taiwanese chronic hepatitis C patients treated with interferon-alpha.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.