Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SWI/SNF chromatin remodeling and human malignancies.

Annual review of pathology - 1 Jan 2015

Masliah-Planchon Julien, Bièche Ivan, Guinebretière Jean-Marc, Bourdeaut Franck, Delattre Olivier

Abstract excerpt

The SWI/SNF complexes, initially identified in yeast 20 years ago, are a family of multi-subunit complexes that use the energy of adenosine triphosphate (ATP) hydrolysis to remodel nucleosomes. Chromatin remodeling processes mediated by the SWI/SNF complexes are critical to the modulation of gene expression across a variety of cellular processes, including stemness, differentiation, and proliferation. The first...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromatin Remodeling and Cancer

Share to Chromosomal Proteins, Non-Histone

Share to SMARCB1 gene

Share to Mutation

Share to Neoplasms

Share to Transcription Factors

Source

Identifiers

PMID: 25387058
DOI: 10.1146/annurev-pathol-012414-040445

Genes

SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SWI/SNF chromatin remodeling and human malignancies.PMID 25387058Read ↗

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.Semantic proximity Read ↗

SWI/SNF chromatin remodeling complexes and cancer.Semantic proximity Read ↗

Chromatin remodeling and cancer: the critical influence of the SWI/SNF complex.Semantic proximity Read ↗

The role of SWI/SNF complexes in digestive system neoplasms.Semantic proximity Read ↗

SWI/SNF nucleosome remodellers and cancer.Semantic proximity Read ↗

The SWI/SNF complex in cancer - biology, biomarkers and therapy.Semantic proximity Read ↗

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities.Semantic proximity Read ↗

The spectrum of SWI/SNF mutations, ubiquitous in human cancers.Semantic proximity Read ↗

Advances in the role of SWI/SNF complexes in tumours.Semantic proximity Read ↗

SWI/SNF chromatin remodeling and cancer.Semantic proximity Read ↗

Hijacking the Chromatin Remodeling Machinery: Impact of<i>SWI/SNF</i>Perturbations in CancerSemantic proximity Read ↗

Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunitiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.