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Article

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities.

Molecular cancer - 21 Feb 2023

Andrades Alvaro, Peinado Paola, Alvarez-Perez Juan Carlos, Sanjuan-Hidalgo Juan, García Daniel J, Arenas Alberto M, Matia-González Ana M, Medina Pedro P

Abstract excerpt

Hematological malignancies are a highly heterogeneous group of diseases with varied molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) chromatin remodeling complexes play significant roles in the regulation of gene expression, being essential for processes such as cell maintenance and differentiation in hematopoietic stem cells. Furthermore, alterations in SWI/SNF complex...

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Identifiers

PMID: 36810086
DOI: 10.1186/s12943-023-01736-8
PMCID: PMC9942420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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