Article
The role of SWI/SNF complexes in digestive system neoplasms.
Medical oncology (Northwood, London, England) - 17 Apr 2024
Liang Hanyun, Zheng Xin, Zhang Xiao, Zhang Yan, Zheng Jie
Abstract excerpt
Chromatin remodeling is a critical step in the DNA damage response, and the ATP-dependent chromatin remodelers are a group of epigenetic regulators that alter nucleosome assembly and regulate transcription factor accessibility to DNA, preventing genomic instability and tumorigenesis caused by DNA damage. The SWI/SNF chromatin remodeling complex is one of them, and mutations in the gene encoding the SWI/SNF...
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