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Article

Detection of allele specific differences in IFNL3 (IL28B) mRNA expression.

BMC medical genetics - 5 Oct 2014

Knapp Susanne, Meghjee Naeem, Cassidy Sorcha, Jamil Khaleel, Thursz Mark

Abstract excerpt

BACKGROUND: Variants of the interferon-lambda3 (IFNL3) gene have been associated with both spontaneous and treatment induced clearance of HCV infection. Attempts to link polymorphisms of the IFNL3 gene with variation in the level of IFNL3 expression have been inconclusive. This is partially due to the difficulty to design assays distinguishing IFNL3 from IFNL2. METHODS: In this study an allele specific real-time...

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Identifiers

PMID: 25287681
DOI: 10.1186/s12881-014-0104-7
PMCID: PMC4411934

Genes

IFNL3
IFNL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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