Article
Systematic review with meta-analysis: do interferon lambda 3 polymorphisms predict the outcome of interferon-therapy in hepatitis B infection?
Alimentary pharmacology & therapeutics - 1 Mar 2014
Galmozzi E, Viganò M, Lampertico P
Abstract excerpt
BACKGROUND: Interferon lambda 3 (IFN-λ3) polymorphisms are the strongest genetic predictor of outcome of hepatitis C virus infection and of response to Pegylated interferon (PegIFN)-based therapy. Whether this holds true for hepatitis B virus (HBV) infection is matter of controversy. AIM: To review the association between host genomics and spontaneous or interferon-induced clearance of HBV with specific reference...
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