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Article

IFNL3 mediates interaction between innate immune cells: Implications for hepatitis C virus pathogenesis.

Innate immunity - 1 Aug 2014

O'Connor Kate S, Ahlenstiel Golo, Suppiah Vijayaprakash, Schibeci Stephen, Ong Adrian, Leung Reynold, van der Poorten David, Douglas Mark W, Weltman Martin D, Stewart Graeme J, Liddle Christopher, George Jacob, Booth David R

Abstract excerpt

Common IFN lambda 3 (IFNL3) variants have been demonstrated to affect spontaneous and treatment-induced clearance of hepatitis C virus (HCV) infection. The functional basis of these genetic variants has yet to be determined. Data examining the effect of IFNL3, specifically, in innate immune cells is lacking. Here, we determined the expression of IFNL3 and its receptor IFNLR1 in blood immune cell subsets and in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24045339
DOI: 10.1177/1753425913503385

Genes

IFNL3
IFNLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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