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Article

Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection.

PloS one - 1 Jan 2013

Fischer Janett, Böhm Stephan, Müller Tobias, Witt Heiko, Sarrazin Christoph, Susser Simone, Migaud Pascal, Schott Eckart, Stewart Graeme, Brodzinski Annika, Fülöp Balazs, van Bömmel Florian, George Jacob, Berg Thomas

Abstract excerpt

BACKGROUND & AIMS: Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or histological baseline parameters. We evaluated whether the interplay of both IFNL3 polymorphisms rs12979860 and rs8099917 together with non-genetic clinical factors...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24204859
DOI: 10.1371/journal.pone.0077530
PMCID: PMC3812277

Genes

IFNL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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