Article
Genetic variation in the raptor gene is associated with overweight but not hypertension in American men of Japanese ancestry.
American journal of hypertension - 1 Apr 2015
Morris Brian J, Carnes Bruce A, Chen Randi, Donlon Timothy A, He Qimei, Grove John S, Masaki Kamal H, Elliott Ayako, Willcox Donald C, Allsopp Richard, Willcox Bradley J
Abstract excerpt
BACKGROUND: The mechanistic target of rapamycin (mTOR) pathway is pivotal for cell growth. Regulatory associated protein of mTOR complex I (Raptor) is a unique component of this pro-growth complex. The present study tested whether variation across the raptor gene (RPTOR) is associated with overweight and hypertension. METHODS: We tested 61 common (allele frequency ≥ 0.1) tagging single nucleotide polymorphisms...
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