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Article

Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.

PLoS genetics - 28 Oct 2010

Sun Chang, Southard Catherine, Witonsky David B, Kittler Ralf, Di Rienzo Anna

Abstract excerpt

The mechanistic target of rapamycin (MTOR) pathway regulates cell growth, energy homeostasis, apoptosis, and immune response. The regulatory associated protein of MTOR encoded by the RPTOR gene is a key component of this pathway. A previous survey of candidate genes found that RPTOR contains mult...

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Source

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Identifiers

PMID: 21060808
DOI: 10.1371/journal.pgen.1001178
PMCID: PMC2965758

Genes

MTOR
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21060808-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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