Inverse Association Between Height-Increasing Alleles and Extreme Longevity in Japanese Women.

doi:10.1093/gerona/glx155

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Inverse Association Between Height-Increasing Alleles and Extreme Longevity in Japanese Women.

The journals of gerontology. Series A, Biological sciences and medical sciences - 17 Apr 2018

Tanisawa Kumpei, Hirose Nobuyoshi, Arai Yasumichi, Shimokata Hiroshi, Yamada Yoshiji, Kawai Hisashi, Kojima Motonaga, Obuchi Shuichi, Hirano Hirohiko, Suzuki Hiroyuki, Fujiwara Yoshinori, Taniguchi Yu, Shinkai Shoji, Ihara Kazushige, Sugaya Maki, Higuchi Mitsuru, Arai Tomio, Mori Seijiro, Sawabe Motoji, Sato Noriko, Muramatsu Masaaki, Tanaka Masashi

Abstract excerpt

Growth hormone (GH)/insulin-like growth factor-1 (IGF-1)/insulin signaling is one of the most plausible biological pathways regulating aging and longevity. Previous studies have demonstrated that several single nucleotide polymorphisms (SNPs) in the GH/IGF-1/insulin signaling-associated genes influence both longevity and adult height, suggesting the possibility of a shared genetic architecture between longevity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Alleles

Share to Body Height

Share to Case-Control Studies

Share to Japan

Share to Longevity

Share to Longitudinal Studies

Source

Open in PubMed

Identifiers

PMID: 28958036
DOI: 10.1093/gerona/glx155

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inverse Association Between Height-Increasing Alleles and Extreme Longevity in Japanese Women.PMID 28958036Read ↗

Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry.Semantic proximity Read ↗

Evaluation of genetic loci influencing adult height in the Japanese population.Semantic proximity Read ↗

Replication study of the association of SNPs in the LHX3-QSOX2 and IGF1 loci with adult height in the Japanese population; wide-ranging comparison of each SNP genotype distribution.Semantic proximity Read ↗

Association of the <i>FOXO3A</i> Locus with Extreme Longevity in a Southern Italian Centenarian StudySemantic proximity Read ↗

Reduced insulin/IGF-1 signalling and human longevity.Semantic proximity Read ↗

The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature.Semantic proximity Read ↗

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults.Semantic proximity Read ↗

Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.Semantic proximity Read ↗

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.Semantic proximity Read ↗

Geographic variation in the polygenic score of height in Japan.Semantic proximity Read ↗

Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.