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Article

Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women.

Cancer causes & control : CCC - 1 Aug 2016

Cheng Ting-Yuan David, Shankar Jyoti, Zirpoli Gary, Roberts Michelle R, Hong Chi-Chen, Bandera Elisa V, Ambrosone Christine B, Yao Song

Abstract excerpt

PURPOSE: Positive energy imbalance and growth factors linked to obesity promote the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (mTOR) pathway. As the obesity-breast cancer associations differ between European American (EA) and African-American (AA) women, we investigated genetic variants in the mTOR pathway and breast cancer risk in these two racial groups. METHODS: We examined 400...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27314662
DOI: 10.1007/s10552-016-0774-x
PMCID: PMC4958603

Genes

CDKAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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