Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity.

Age (Dordrecht, Netherlands) - 1 Jun 2013

Benigni Ariela, Orisio Silvia, Noris Marina, Iatropoulos Paraskevas, Castaldi Davide, Kamide Kei, Rakugi Hiromi, Arai Yasumichi, Todeschini Marta, Ogliari Giulia, Imai Enyu, Gondo Yasuyuki, Hirose Nobuyoshi, Mari Daniela, Remuzzi Giuseppe

Abstract excerpt

Longevity phenotype in humans results from the influence of environmental and genetic factors. Few gene polymorphisms have been identified so far with a modest effect on lifespan leaving room for the search of other players in the longevity game. It has been recently demonstrated that targeted di...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Linkage Disequilibrium

Share to Longevity

Share to Receptor, Angiotensin, Type 1

Source

Open in PubMed Open full text

Identifiers

PMID: 22569962
DOI: 10.1007/s11357-012-9408-8
PMCID: PMC3636412

Genes

AGTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22569962-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity.PMID 22569962Read ↗

The genetics of exceptional longevity: Insights from centenarians.Semantic proximity Read ↗

Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.Semantic proximity Read ↗

Genetic signatures of exceptional longevity in humans.Semantic proximity Read ↗

Understanding the determinants of exceptional longevity.Semantic proximity Read ↗

The genetics of exceptional human longevity.Semantic proximity Read ↗

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart diseaseSemantic proximity Read ↗

Rare genetic coding variants associated with human longevity and protection against age-related diseases.Semantic proximity Read ↗

Genetic Signatures of Centenarians: Implications for Achieving Successful Aging.Semantic proximity Read ↗

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians.Semantic proximity Read ↗

Meta‐analysis of genetic variants associated with human exceptional longevity.Semantic proximity Read ↗

Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics.Semantic proximity Read ↗

The genetics of exceptional human longevity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.