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Article

Effect of endogenous Hsp104 chaperone in yeast models of sporadic and familial Parkinson's disease.

The international journal of biochemistry & cell biology - 1 Oct 2014

Gade Vamshidhar R, Kardani Jay, Roy Ipsita

Abstract excerpt

Molecular chaperones constitute a major component of the cellular stress response machinery in neurodegenerative diseases, many of which are characterized by the misfolding and aggregation of endogenous cellular proteins into generic amyloid macrostructures. Heterologous expression of the yeast protein remodelling factor Hsp104 has been proposed as a possible therapeutic approach in such disease conditions....

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PMID: 25161148
DOI: 10.1016/j.biocel.2014.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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