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Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

20 Apr 2013

Abstract excerpt

Several neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), or prion diseases, are known for their intimate association with protein misfolding and aggregation. These disorders are characterized by the loss of specific neuronal populations in the brain and are highly associated with aging, suggesting a decline in...

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PMID: 23600759
DOI: 10.1111/jnc.12271

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