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Article

APOE genotype-dependent modulation of astrocyte chemokine CCL3 production.

Glia - 1 Jan 2015

Cudaback Eiron, Yang Yue, Montine Thomas J, Keene C Dirk

Abstract excerpt

Apolipoprotein E (apoE) is well known as a regulator of cholesterol homeostasis, and is increasingly recognized to play a prominent role in the modulation of innate immune response, including cell-to-cell communication and migration. Alzheimer's disease (AD) is a slowly progressive neurodegenerative disorder characterized by neuroinflammation that appears to be an important component of the pathophysiology of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25092803
DOI: 10.1002/glia.22732
PMCID: PMC4237722

Genes

APOE
CCL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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