Article
Polymorphisms in the IFNL3/IL28B gene and hepatitis C: from adults to children.
World journal of gastroenterology - 28 Jul 2014
Indolfi Giuseppe, Azzari Chiara, Resti Massimo
Abstract excerpt
The purpose of the present review is to summarise the current knowledge on the association between single nucleotide polymorphisms (SNPs) in the interferon L3 (IFNL3) gene and hepatitis C virus (HCV) infection in children. Many studies in adults have demonstrated that genetic variation in IFNL3 is a strong predictor of the virological response in treatment-naive patients with HCV genotype 1 who were treated with...
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