Article

IFN-λ4 is associated with increased risk and earlier occurrence of gastrointestinal, respiratory and malarial infections in Malian children

2020-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Genetic polymorphisms within the IFNL3 / IFNL4 genomic region, which encodes type III interferons, have been strongly associated with impaired clearance of hepatitis C virus (HCV) infection. We hypothesized that type III interferons might be important for the immune response to other pathogens as well. In a cohort of 914 Malian children, we analyzed episodes of malaria, gastrointestinal and re...

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Literature Corpus work: 34b20905-1e17-57f7-99d7-ef823eae5a70
DOI: 10.1101/2020.02.24.962688

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