Article
IFNL3 polymorphisms and HCV infection in patients with beta thalassemia.
Annals of hepatology - 1 Jan 2000
Origa Raffaella, Marceddu Giuseppe, Danjou Fabrice, Perseu Luciana, Satta Stefania, Demartis Franca Rosa, Piga Antonio, Longo Filomena, Lai Maria-Eliana, Vacquer Stefania, Galanello Renzo
Abstract excerpt
UNLABELLED: BACKGROUND AND RATIONALE FOR THE STUDY: Genome-wide association studies have identified host genetic variation to be critical for spontaneous clearance and treatment response in patients infected with hepatitis C virus. Recently, the role of the IFNL3 polymorphisms in influencing the spontaneous clearance of HCV, the response to interferon and the progression of liver fibrosis, was also demonstrated...
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