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Article

Can IFNL3 polymorphisms predict response to interferon/ribavirin treatment in hepatitis C patients with genotype 3?

The Journal of general virology - 1 Oct 2016

Mansoor Sajid, Riaz Sana, Kausar Sara, Muhammad Din Sadia, Javed Aneela, Sultan Aneesa, Mansoor Atika

Abstract excerpt

Favourable genotypes of IFNL3 polymorphism CC for rs12979860 and TT for rs8099917 are strongly associated with the interferon/ribavirin treatment outcome in hepatitis C virus (HCV) patients with genotypes 1 and 4. Contrarily, conflicting results have been reported for patients with HCV genotypes 2 and 3. Therefore, we sought to investigate the association between IFNL3 with sustained virological response (SVR)...

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Identifiers

PMID: 27498543
DOI: 10.1099/jgv.0.000572

Genes

IFNL3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Can IFNL3 polymorphisms predict response to interferon/ribavirin treatment in hepatitis C patients with genotype 3?PMID 27498543Read ↗

IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection.Semantic proximity Read ↗

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The relationships between IFNL4 genotype, intrahepatic interferon-stimulated gene expression and interferon treatment response differs in HCV-1 compared with HCV-3.Semantic proximity Read ↗

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