Article
Interleukin 28B rs12979860 single-nucleotide polymorphism predicts spontaneous clearance of hepatitis C virus in children.
Journal of pediatric gastroenterology and nutrition - 1 May 2014
Indolfi Giuseppe, Mangone Giusi, Calvo Pier Luigi, Bartolini Elisa, Regoli Marta, Serranti Daniele, Calitri Carmelina, Tovo Pier-Angelo, de Martino Maurizio, Azzari Chiara, Resti Massimo
Abstract excerpt
OBJECTIVE: Recent genome-wide association studies performed in adults correlated single-nucleotide polymorphisms (SNPs rs12979860 and rs8099917) located on chromosome 19, upstream of the interleukin 28B gene, with spontaneous clearance of hepatitis C virus and with response to treatment with paginated interferon and ribavirin. The aim of the present collaborative study was to evaluate the rs12979860 SNP in a...
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