Influence of IFNL3.rs12979860 and IFNL4.ss469415590 polymorphism on clearance of hepatitis C virus infection among Egyptians.

doi:10.1007/s12072-015-9619-z

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Article

Influence of IFNL3.rs12979860 and IFNL4.ss469415590 polymorphism on clearance of hepatitis C virus infection among Egyptians.

Hepatology international - 1 Apr 2015

Knapp Susanne, Zakaria Zainab, Hashem Mohamed, Zaghla Hassan, Khakoo Salim I, Waked Imam, Thursz Mark, Abdelwahab Sayed F

Abstract excerpt

BACKGROUND/PURPOSE: Single-nucleotide polymorphisms (SNPs) around the interferon lambda 3 (IFNL3; also known as interleukin 28B; IL28B) gene are associated with spontaneous hepatitis C virus (HCV) clearance. Interferon lambda 4 (IFNL4).ss469415590, in linkage disequilibrium (LD) with IFNL3.rs12979860 among the Caucasian population, has recently been identified as a potential functional variant. Our objective was...

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PMID: 25788203
DOI: 10.1007/s12072-015-9619-z

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IFNL3

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