Article
SNPs of the IFNL favour spontaneous clearance of HCV infection in children.
Pediatric research - 1 May 2022
Mangone Giusi, Serranti Daniele, Bartolini Elisa, Vigna Veronica, Mastrangelo Greta, Ricci Silvia, Trapani Sandra, Azzari Chiara, Resti Massimo, Indolfi Giuseppe
Abstract excerpt
BACKGROUND: Both spontaneous and treatment-induced clearance of hepatitis C virus (HCV) in adults have been associated with genetic polymorphisms in the interferon-λ genes. The aim of the present study was to confirm the association between the rs12979860 and evaluate the association between the rs368234815 and the rs4803217 single-nucleotide polymorphisms (SNPs) of the interferon-λ genes and the outcome of the...
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