Article
dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes.
Nucleic acids research - 1 Aug 2014
Korenjak Michael, Kwon Eunjeong, Morris Robert T, Anderssen Endre, Amzallag Arnaud, Ramaswamy Sridhar, Dyson Nicholas J
Abstract excerpt
dREAM complexes represent the predominant form of E2F/RBF repressor complexes in Drosophila. dREAM associates with thousands of sites in the fly genome but its mechanism of action is unknown. To understand the genomic context in which dREAM acts we examined the distribution and localization of Drosophila E2F and dREAM proteins. Here we report a striking and unexpected overlap between dE2F2/dREAM sites and binding...
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