Article
Ectopic expression of DREF induces DNA synthesis, apoptosis, and unusual morphogenesis in the Drosophila eye imaginal disc: possible interaction with Polycomb and trithorax group proteins.
Molecular and cellular biology - 1 Nov 2001
Hirose F, Ohshima N, Shiraki M, Inoue Y H, Taguchi O, Nishi Y, Matsukage A, Yamaguchi M
Abstract excerpt
The promoters of Drosophila genes encoding DNA replication-related proteins contain transcription regulatory element DRE (5'-TATCGATA) in addition to E2F recognition sites. A specific DRE-binding factor, DREF, positively regulates DRE-containing genes. In addition, it has been reported that DREF can bind to a sequence in the hsp70 scs' chromatin boundary element that is also recognized by boundary...
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