Article
RBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexes.
Molecular and cellular biology - 1 Nov 2012
Korenjak Michael, Anderssen Endre, Ramaswamy Sridhar, Whetstine Johnathan R, Dyson Nicholas J
Abstract excerpt
The retinoblastoma (RB) family of proteins regulate transcription. These proteins lack intrinsic DNA-binding activity but are recruited to specific genomic locations through interactions with sequence-specific DNA-binding factors. The best-known target of RB protein (pRB) is the E2F transcription factor; however, many other chromatin-associated proteins have been described that may allow RB family members to act...
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