Article
Drosophila Mi-2 negatively regulates dDREF by inhibiting its DNA-binding activity.
Molecular and cellular biology - 1 Jul 2002
Hirose Fumiko, Ohshima Nobuko, Kwon Eun-Jeong, Yoshida Hideki, Yamaguchi Masamitsu
Abstract excerpt
Drosophila melanogaster DNA replication-related element (DRE) factor (dDREF) is a transcriptional regulatory factor required for the expression of genes carrying the 5'-TATCGATA DRE. dDREF has been reported to bind to a sequence in the chromatin boundary element, and thus, dDREF may play a part in regulating insulator activity. To generate further insights into dDREF function, we carried out a Saccharomyces...
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