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Article

BDNF Val66Met genotype interacts with childhood adversity and influences the formation of hippocampal subfields.

Human brain mapping - 1 Dec 2014

Frodl Thomas, Skokauskas Norbert, Frey Eva-Maria, Morris Derek, Gill Michael, Carballedo Angela

Abstract excerpt

Childhood stress and genetic factors like the Val66MET polymorphism of the brain derived neurotrophic factor (BDNF) gene are associated with a higher risk for developing major depressive disorder (MDD) and might also influence hippocampal changes. The aim of this study was to determine which hippocampal dentate gyrus and cornu ammonis subfields are altered in MDD compared to healthy controls and which subfields...

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Source

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Identifiers

PMID: 25044977
DOI: 10.1002/hbm.22584
PMCID: PMC6869047

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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