Article
Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.
PloS one - 1 Jan 2014
Almlöf Jonas Carlsson, Lundmark Per, Lundmark Anders, Ge Bing, Pastinen Tomi, Goodall Alison H, Cambien François, Deloukas Panos, Ouwehand Willem H, Syvänen Ann-Christine
Abstract excerpt
We applied genome-wide allele-specific expression analysis of monocytes from 188 samples. Monocytes were purified from white blood cells of healthy blood donors to detect cis-acting genetic variation that regulates the expression of long non-coding RNAs. We analysed 8929 regions harboring genes for potential long non-coding RNA that were retrieved from data from the ENCODE project. Of these regions, 60% were...
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