Article
Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes.
PLoS genetics - 1 Jan 2013
Garnier Sophie, Truong Vinh, Brocheton Jessy, Zeller Tanja, Rovital Maxime, Wild Philipp S, Ziegler Andreas, Munzel Thomas, Tiret Laurence, Blankenberg Stefan, Deloukas Panos, Erdmann Jeannette, Hengstenberg Christian, Samani Nilesh J, Schunkert Heribert, Ouwehand Willem H, Goodall Alison H, Cambien François, Trégouët David-Alexandre
Abstract excerpt
In order to assess whether gene expression variability could be influenced by several SNPs acting in cis, either through additive or more complex haplotype effects, a systematic genome-wide search for cis haplotype expression quantitative trait loci (eQTL) was conducted in a sample of 758 individuals, part of the Cardiogenics Transcriptomic Study, for which genome-wide monocyte expression and GWAS data were...
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