Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

doi:10.1371/journal.pone.0010693

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Article

Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

PloS one - 18 May 2010

Zeller Tanja, Wild Philipp, Szymczak Silke, Rotival Maxime, Schillert Arne, Castagne Raphaele, Maouche Seraya, Germain Marine, Lackner Karl, Rossmann Heidi, Eleftheriadis Medea, Sinning Christoph R, Schnabel Renate B, Lubos Edith, Mennerich Detlev, Rust Werner, Perret Claire, Proust Carole, Nicaud Viviane, Loscalzo Joseph, Hübner Norbert, Tregouet David, Münzel Thomas, Ziegler Andreas, Tiret Laurence, Blankenberg Stefan, Cambien François

Abstract excerpt

BACKGROUND: Variability of gene expression in human may link gene sequence variability and phenotypes; however, non-genetic variations, alone or in combination with genetics, may also influence expression traits and have a critical role in physiological and disease processes. METHODOLOGY/PRINCIPAL FINDINGS: To get better insight into the overall variability of gene expression, we assessed the transcriptome of...

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PMID: 20502693
DOI: 10.1371/journal.pone.0010693
PMCID: PMC2872668

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