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Article

X Chromosome of female cells shows dynamic changes in status during human somatic cell reprogramming.

Stem cell reports - 3 Jun 2014

Kim Kun-Yong, Hysolli Eriona, Tanaka Yoshiaki, Wang Brandon, Jung Yong-Wook, Pan Xinghua, Weissman Sherman Morton, Park In-Hyun

Abstract excerpt

Induced pluripotent stem cells (iPSCs) acquire embryonic stem cell (ESC)-like epigenetic states, including the X chromosome. Previous studies reported that human iPSCs retain the inactive X chromosome of parental cells, or acquire two active X chromosomes through reprogramming. Most studies investigated the X chromosome states in established human iPSC clones after completion of reprogramming. Thus, it is still...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24936474
DOI: 10.1016/j.stemcr.2014.04.003
PMCID: PMC4050354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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