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A temporally controlled sequence of X-chromosome inactivation and reactivation defines female mouse <i>in vitro</i> germ cells with meiotic potential

2021-08-11

Abstract excerpt

The early mammalian germ cell lineage is characterized by extensive epigenetic reprogramming, which is required for the maturation into functional eggs and sperm. In particular, the epigenome needs to be reset before parental marks can be established and then transmitted to the next generation. In the female germ line, reactivation of the inactive X-chromosome is one of the most prominent epigenetic reprogramming...

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Literature Corpus work
dc770245-601f-5e2b-a0b2-e32a3c3a1865
DOI
10.1101/2021.08.11.455976
Open publication

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A temporally controlled sequence of X-chromosome inactivation and reactivation defines female mouse <i>in vitro</i> germ cells with meiotic potentialDOI 10.1101/2021.08.11.455976
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