Article
Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans.
Diabetologia - 1 Jul 2014
Ren Jie, Xiang Anny H, Trigo Enrique, Takayanagi Miwa, Beale Elizabeth, Lawrence Jean M, Hartiala Jaana, Richey Joyce M, Allayee Hooman, Buchanan Thomas A, Watanabe Richard M
Abstract excerpt
AIMS/HYPOTHESIS: MTNR1B is a type 2 diabetes susceptibility locus associated with cross-sectional measures of insulin secretion. We hypothesised that variation in MTNR1B contributes to the absolute level of a diabetes-related trait, temporal rate of change in that trait, or both. METHODS: We test...
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