The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.

doi:10.3389/fendo.2024.1398687

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The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.

Frontiers in endocrinology - 1 Jan 2024

Zhang Sijie, Bian Wenxuan, Wang Yan, Shen Min, Qian Yu, Dai Hao, Zheng Shuai, Fu Qi, Xu Kuanfeng, Yang Tao, Jiang Hemin

Abstract excerpt

Objective: This study aims to investigate the associations between MTNR1B rs724030 A>G variant and prediabetes risk, along with their correlations with clinical features, including plasma glucose and serum insulin levels during oral glucose tolerance test (OGTT), islet function, insulin resistance, and plasma lipid levels. In particular, we investigated whether there are sex dimorphisms in the impact of this...

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Identifiers

PMID: 39886031
DOI: 10.3389/fendo.2024.1398687
PMCID: PMC11779613

Genes

MTNR1B

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