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Article

Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish.

Diabetologia - 1 Feb 2015

Maruthur Nisa M, Clark Jeanne M, Fu Mao, Linda Kao W H, Shuldiner Alan R

Abstract excerpt

AIMS/HYPOTHESIS: SLC30A8 encodes a zinc transporter in the beta cell; individuals with a common missense variant (rs13266634; R325W) in SLC30A8 demonstrate a lower early insulin response to glucose and an increased risk of type 2 diabetes. We hypothesised that zinc supplementation may improve ins...

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Identifiers

PMID: 25348609
DOI: 10.1007/s00125-014-3419-1
PMCID: PMC4505931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25348609-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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