Article
Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes.
The Journal of clinical endocrinology and metabolism - 1 Mar 2015
Black Mary Helen, Wu Jun, Takayanagi Miwa, Wang Nan, Taylor Kent D, Haritunians Talin, Trigo Enrique, Lawrence Jean M, Watanabe Richard M, Buchanan Thomas A, Xiang Anny H
Abstract excerpt
CONTEXT: Peroxisome proliferator-activated receptor gamma (PPARG) is a susceptibility locus for type 2 diabetes mellitus (T2DM). Although cross-sectional associations have been reported, primarily for Pro12Ala, few longitudinal studies in nondiabetic populations have been conducted. OBJECTIVE: This study aimed to examine whether and to what extent variation in PPARG is associated with longitudinal changes in...
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