Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.

doi:10.1007/s00439-014-1439-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.

Human genetics - 1 Aug 2014

Ellis Jaclyn, Lange Ethan M, Li Jin, Dupuis Josee, Baumert Jens, Walston Jeremy D, Keating Brendan J, Durda Peter, Fox Ervin R, Palmer Cameron D, Meng Yan A, Young Taylor, Farlow Deborah N, Schnabel Renate B, Marzi Carola S, Larkin Emma, Martin Lisa W, Bis Joshua C, Auer Paul, Ramachandran Vasan S, Gabriel Stacey B, Willis Monte S, Pankow James S, Papanicolaou George J, Rotter Jerome I, Ballantyne Christie M, Gross Myron D, Lettre Guillaume, Wilson James G, Peters Ulrike, Koenig Wolfgang, Tracy Russell P, Redline Susan, Reiner Alex P, Benjamin Emelia J, Lange Leslie A

Abstract excerpt

C-reactive protein (CRP) is a heritable biomarker of systemic inflammation and a predictor of cardiovascular disease (CVD). Large-scale genetic association studies for CRP have largely focused on individuals of European descent. We sought to uncover novel genetic variants for CRP in a multiethnic sample using the ITMAT Broad-CARe (IBC) array, a custom 50,000 SNP gene-centric array having dense coverage of over...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to C-Reactive Protein

Share to Cardiovascular Diseases

Share to CD36 Antigens

Share to Genetic Loci

Share to Genetics, Population

Share to Meta-Analysis as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 24643644
DOI: 10.1007/s00439-014-1439-z
PMCID: PMC4104766

Genes

CRP
APOE
APOC1
GCKR
LEPR
NLRP3
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.PMID 24643644Read ↗

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.Semantic proximity Read ↗

Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts.Semantic proximity Read ↗

Association of exome sequences with plasma C-reactive protein levels in >9000 participants.Semantic proximity Read ↗

Genetic analysis of over half a million people characterises C-reactive protein loci.Semantic proximity Read ↗

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.Semantic proximity Read ↗

Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).Semantic proximity Read ↗

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.Semantic proximity Read ↗

C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.Semantic proximity Read ↗

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.Semantic proximity Read ↗

Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and diseasesSemantic proximity Read ↗

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.