Article
Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and diseases
2021-08-05
Abstract excerpt
We performed the largest genome-wide meta-analysis (GWAMA) (Max N=26,494) of the levels of 184 cardiovascular-related plasma protein levels to date and reported 592 independent loci (pQTL) associated with the level of at least one protein (1308 significant associations, median 6 per protein). We estimated that only between 8-37% of testable pQTL overlap with established expression quantitative trait loci (eQTL) us...
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Identifiers and source
- Literature Corpus work
- 6d074634-f7a2-5b59-8c9e-b9a0083ddbc8
- DOI
- 10.1101/2021.08.03.21261494