Article
Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).
Blood - 6 Jan 2011
Wassel Christina L, Lange Leslie A, Keating Brendan J, Taylor Kira C, Johnson Andrew D, Palmer Cameron, Ho Lindsey A, Smith Nicholas L, Lange Ethan M, Li Yun, Yang Qiong, Delaney Joseph A, Tang Weihong, Tofler Geoffrey, Redline Susan, Taylor Herman A, Wilson James G, Tracy Russell P, Jacobs David R, Folsom Aaron R, Green David, O'Donnell Christopher J, Reiner Alexander P
Abstract excerpt
Several common genomic loci, involving various immunity- and metabolism-related genes, have been associated with plasma fibrinogen in European Americans (EAs). The genetic determinants of fibrinogen in African Americans (AAs) are poorly characterized. Using a vascular gene-centric array in 23,634 EA and 6657 AA participants from 6 studies comprising the Candidate Gene Association Resource project, we examined the...
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