Article
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
American journal of human genetics - 1 May 2008
Ridker Paul M, Pare Guillaume, Parker Alex, Zee Robert Y L, Danik Jacqueline S, Buring Julie E, Kwiatkowski David, Cook Nancy R, Miletich Joseph P, Chasman Daniel I
Abstract excerpt
Although elevated levels of C-reactive protein (CRP) independently predict increased risk of development of metabolic syndrome, diabetes, myocardial infarction, and stroke, comprehensive analysis of the influence of genetic variation on CRP is not available. To address this issue, we performed a genome-wide association study among 6345 apparently healthy women in which we evaluated 336,108 SNPs as potential...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.