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Article

Lack of association of the caspase-12 long allele with community-acquired pneumonia in people of African descent.

PloS one - 1 Jan 2014

Chen Jiwang, Wilson Esther S, Dahmer Mary K, Quasney Michael W, Waterer Grant W, Feldman Charles, Wunderink Richard G

Abstract excerpt

Community-acquired pneumonia (CAP) is a common cause of sepsis. Active full-length caspase-12 (CASP12L), confined to the people of African descent, has been associated with increased susceptibility to and mortality from severe sepsis. The objective of this study was to determine whether CASP12L was a marker for susceptibility and/or severity of CAP. We examined three CAP cohorts and two control populations: 241...

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Identifiers

PMID: 24586588
DOI: 10.1371/journal.pone.0089194
PMCID: PMC3935862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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