CASPASE-12 and rheumatoid arthritis in African-Americans.

doi:10.1007/s00251-014-0762-9

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Article

CASPASE-12 and rheumatoid arthritis in African-Americans.

Immunogenetics - 1 Apr 2014

Marshall Laura, Obaidullah Mohammad, Fuchs Trista, Fineberg Naomi S, Brinkley Garland, Mikuls Ted R, Bridges S Louis, Hermel Evan

Abstract excerpt

CASPASE-12 (CASP12) has a downregulatory function during infection and thus may protect against inflammatory disease. We investigated the distribution of CASP12 alleles (#rs497116) in African-Americans (AA) with rheumatoid arthritis (RA). CASP12 alleles were genotyped in 953 RA patients and 342 controls. Statistical analyses comparing genotype groups were performed using Kruskal-Wallis non-parametric ANOVA with...

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PMID: 24515649
DOI: 10.1007/s00251-014-0762-9
PMCID: PMC4139147

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