Article
Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Sept 2015
Mills Tara C, Chapman Stephen, Hutton Paula, Gordon Anthony C, Bion Julian, Chiche Jean-Daniel, Holloway Paul A H, Stüber Frank, Garrard Chris S, Hinds Charles J, Hill Adrian V S, Rautanen Anna
Abstract excerpt
BACKGROUND: Sepsis is an increasingly common condition, which continues to be associated with unacceptably high mortality. A large number of association studies have investigated susceptibility to, or mortality from, sepsis for variants in the functionally important immune-related gene MBL2. These studies have largely been underpowered and contradictory. METHODS: We genotyped and analyzed 4 important MBL2 single...
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